Letrozole: Description of the Drug

Letrozole is a medication primarily used in the treatment of certain types of breast cancer. It is classified as an aromatase inhibitor, which means it works by reducing the amount of estrogen produced in the body, thereby slowing or stopping the growth of hormone-sensitive tumors.

Mechanism of Action

Letrozole functions by inhibiting the aromatase enzyme, which is crucial for the conversion of androgens to estrogens in postmenopausal women. By lowering estrogen levels, letrozole can help shrink tumors or prevent their recurrence. This action is particularly beneficial for patients with:

Hormone receptor-positive breast cancer
Early-stage breast cancer following surgery
Advanced breast cancer that is hormone receptor-positive

Indications

The primary indications for letrozole include:

Treatment of early breast cancer after surgery.
Treatment of advanced breast cancer in postmenopausal women.
As part of fertility treatment protocols in certain conditions.

Dosage and Administration

The standard dosage of letrozole is typically 2.5 mg once daily. However, it is essential for patients to follow their healthcare provider’s instructions regarding dosage and duration of therapy.

Possible Side Effects

Like any medication, letrozole may cause side effects. Commonly reported side effects include:

Hot flashes
Joint pain or stiffness
Nausea
Fatigue
Bone thinning (osteoporosis)

Drug Interactions

Patients should inform their healthcare providers about all medications they are taking, as letrozole can interact with:

Estrogen supplements
Other cancer treatments
Certain antifungal medications

FAQs about Letrozole

1. Who should not use letrozole?

Patients who are pregnant, breastfeeding, or https://letrozolebuy.com/prod/letrozol-zentiva-filmtabletten-2-5mg-100-stuck/ have a known hypersensitivity to letrozole should avoid this medication.

2. How long will I need to take letrozole?

The duration of treatment varies based on individual circumstances, but it is often prescribed for five years for early-stage breast cancer.

3. Can letrozole be taken with food?

Letrozole can be taken with or without food, but it is advisable to take it at the same time each day for consistency.

Conclusion

Letrozole has become a vital medication in the management of hormone-sensitive breast cancer. Its ability to effectively lower estrogen levels provides a significant therapeutic benefit for many patients. As always, discussing potential benefits and risks with a healthcare professional is crucial for anyone considering or currently using this medication.